When do blood glucose concentrations typically reach their lowest point after delivery?

Blood glucose concentrations in newborns typically reach their lowest point within the first several hours after birth, most commonly around 1 to 2 hours postpartum. This period is characterized by a physiological adjustment as the newborn transitions from the placental source of glucose to independent feeding. In this timeframe, many infants experience a significant drop in glucose levels due to several factors, including the cessation of maternal glucose supply and adaptations of the newborn's metabolic processes.

Monitoring blood glucose levels during this critical time is essential, especially for infants at risk for hypoglycemia—such as those born to mothers with diabetes or preterm infants—as it allows caregivers to intervene promptly if necessary. Recognizing this pattern helps ensure that appropriate measures are taken to support the infant's nutritional and metabolic needs immediately following delivery.